## page was renamed from Biochemistry and Molecular Biology
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#language en

||<style="border-width: 0px; border-bottom-width: 0px; vertical-align: top; text-align: right; color: #BDB76B; width:35%;" tablewidth="98%"> [[JSI|Home]] ||<style="border-width: 0px; width:%; text-align: left; color:#BDB76B; border-width: 0px; vertical-align: top; background:#"> [[Research departments]]<<BR>>[[Centres]]<<BR>>[[Administration and support units]] <<BR>><<BR>>||

||<style="border-width: 0px; vertical-align: top; text-align: right; font-size: 85%; line-height: 150% ; color: #606060; width:35%;" tablewidth="98%">{{attachment:B/Stefan.jpg}} <<BR>><<BR>> ''' The core of the Department consists of the program groups “proteolysis and its regulation” and “structural biology”. Both groups are focused on protease research.  Proteases play key roles in a number of cellular processes and their regulation by catalyzing the hydrolysis of peptide bonds in proteins, thereby  modulating protein properties by activating or inactivating them. In addition, proteases degrade superfluous, damaged or incorrectly folded  proteins. Protease activity requires strict regulation in order to prevent harmful and excessive protein degradation. The activity is often regulated through the action of small protein molecules – inhibitors, which block protease activities. In a number of diseases the balance between the enzymes and their inhibitors is distorted. In addition, proteases also play an important role in cell death. <<BR>><<BR>> ''' ||<style="border-width: 0px; width:65%; text-align: left; color:#404040; vertical-align: top; BORDER-LEFT-WIDTH: 2px; background:#"> <<Include(/Desno)>> <<BR>>||

||<style="border-width: 0px; BORDER-top-WIDTH: 1px; text-align: center; color: #000000;"tablewidth="98%">~-J. Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia, Telephone: +386 1 477 39 00<<BR>> info@ijs.si  -~ ||