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> '''~- In their wisdom, the creators of an Institute concerned with nuclear technology saw fit to establish a department of radiation biology. At that time, the small number of well characterized proteolytic enzymes provided convenient tools with which to study the effects of radiation on biological materials. Although this general research area never led very far, the discovery, characterization and function of proteolytic enzymes and their inhibitors has formed the basis of a significant programme of research within its successor, the department of biochemistry and molecular biology. <
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> The discovery, at the Institute, of new proteinases and inhibitors in animals and plants has contributed to the current recognition of the great variety of these enzymes, their classification into families, and their importance in health and disease. Only recently, a completely new family of proteinase inhibitors has been discovered in the department. One of the members, equistatin, comes from the sea anemone, while another, on the basis of a quite unexpected discovery, is thought to play an important role in the immune response against foreign proteins. -~''' <
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>'''MOLECULAR BIOLOGY AND BIOTECHNOLOGY''' <
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>|| ||~-J. Stefan Institute, Jamova 39, 1000 Ljubljana, Slovenia, Telephone: +386 1 477 39 00<
> info@ijs.si -~ ||